Therapeutic apheresis in infectious diseasesVirtually no infectious diseases are not accompanied by a significant intoxication, and, usually, it determines the severity of the condition being the main mechanism tanatogenesis significantly affecting the overall outcome. The structure consists of endotoxemia bacterial endo-and exotoxins, products entering the circulation of inflammation and tissue destruction of the primary foci of inflammation secondary metabolic disorders such as, as mentioned above in the description of septic complications.
Heavy endotoxemia causes toxic secondary immunodeficiency, even more debilitating infection of the patient's resistance, inhibits the production of specific antibodies. All this is particularly acute determines the need for not only detoxification at the height of the manifestations of endogenous intoxication, but also measures to immune stimulation. Hemosorption can provide not only detoxification, but also capture and binding of various infectious agents, but can not restore the immune defenses. The latter can be successfully achieved with plasma exchange.